Audio-Digest Foundation: emergency-medicine

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Audio-Digest FoundationEmergency Medicine


Volume 24, Issue 11
June 7, 2007

The following is an abstracted summary, not a verbatim transcript, of the lectures/discussions on this audio program. If, after reviewing this written summary, you would like to hear the contents and/or earn CME/CE credit:

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PROCEDURES IN THE ED

COMMON PROBLEMS IN THE ED Joseph R. Lex, Jr, MD, Assistant Professor of Emergency Medicine, Temple University School of Medicine, Philadelphia, PA
10 most common problems: foreign body in eye; nose bleed; hit in mouth; cut hand; stray dog bite; broken bone; stepped on nail; severe back pain; strep throat; bronchitis returned
Hand injuries: account for 1 in 20 emergency department (ED) visits; men more than women; 60% occur in 16 to 32 yr age group; 60% lacerations; 10% fractures, most commonly distal phalanx of long finger; 5 studies confirm no improvement in rate of hand infections with cephalexin, compared to placebo; appropriate cleaning of hand wound sufficient; antibiotic use not beneficial; common practice to irrigate with 1% povidone/iodine (Betadine) solution (dilute 10% concentrate), but this is still 100% cytotoxic, as is hydrogen peroxide; 0.001% povidone/iodine bactericidal, not cytotoxic; do not soak wounds—soaking in water increases bacterial count; soaking in 1% povidone/iodine does not change bacterial count; irrigation—no difference in infection rate between tap water irrigation and “sterile solutions”; stitches not required—for lacerations 2 cm in length; study data show no difference in cosmesis or time to return to work; in study, one sutured wound became infected, no unsutured wounds infected; savings in cost, pain, time, revisits to ED; hand bites—referral bias; infected hands seen in ED from human, dog, and cat bites; infections polymicrobial (Pasteurella multocida common in dog and cat bites); treat with cephalosporins
Foreign body in eye: history of pain, tearing, foreign body sensation; if light bothersome, patient has light sensitivity; true, deep pain from light considered photophobia; caused by trauma or extended contact lens use; distinguish redness on physical examination (bulbar vs palpebral conjunctiva); if palpebral, think conjunctivitis; visual acuity—normal with simple foreign body; if not normal, consider deep, complex foreign body, perforation, or other cause; with fluorescein or cobalt blue under Wood’s lamp, dye uptake shows corneal epithelial cells; have patient read Snellen chart through pinhole device or hole poked in paper
Corneal abrasions: series of vertical abrasions indicative of foreign body embedded in upper lid; Sidell’s test (clear stream through fluorescein) indicative of corneal perforation; pearls—topical anesthetic; cycloplegic 20 to 30 min before examination; slit lamp, Wood’s lamp with fluorescein, or “poor man’s slit lamp” (have patient lie on back, focus on fluorescent ceiling light so tube reflects on cornea, move head side to side); dendrite indicative of herpes infection; remove contact lens before using fluorescein; common practice to have patients immunized with tetanus toxoid after corneal abrasion, but no documented cases of tetanus from corneal abrasion; topical anesthesia—do not send patients home with topical anesthetic (causes secondary keratitis; compromises healing); proparacaine not irritating, effective in 20 sec, lasts 20 to 30 min, and costs $15 per bottle; tetracaine stings, takes longer to become effective, lasts few minutes longer, costs same as proparacaine; irrigation—use neutral solution; if pH paper not available, use pH square from urine dipstick; if Morgan lenses not available for rapid irrigation, use nasal prongs from oxygen tubing (drape over bridge of nose, hook other end of tubing to intravenous [IV] bag); patching—4 of 6 studies show no difference between patching and not patching; other 2 found patching made patient feel worse; no difference in complications; let patient decide; antibiotics—data do not show antibiotics effective for simple corneal abrasions; most data show antibiotics impede healing; if necessary, use least expensive (sulfacetamide); use antibiotic if contact lens caused scratch (often become infected with Pseudomonas; treat with ciprofloxacin); avoid neomycin (causes severe contact dermatitis in 5% of population)
Eye drops: nonsteroidal anti-inflammatory drug (NSAID) eye drops offer no provable benefit, and expensive; cycloplegics paralyze ciliary muscle, relieve photophobia and pain; mydriatics cause pupil dilation; difficult to separate; color code for drops (solution in vial with red cap dilates pupil, in green cap, shrinks pupil); iris color can affect response; iris color sympathetically mediated; damage to sympathetic system before color fully developed can cause permanently light blue iris; clinical studies of patients with corneal abrasions indicate no difference (in pain, healing, rate of complications) between using simple lubrication, home atropine, NSAID drops, or home atropine plus NSAID drops; half-life of most drops 20 min, so frequent application required (eg, herpes keratitis); drops washed out quickly; little advantage to using ointment
Nosebleeds: occur in young children and older adults; seasonal variation (more frequent in cold months); many drugs predispose patients to nosebleeds; 98% should be treated by nonotolaryngologists; first apply constant pressure (speaker uses 4 tongue depressors taped with two 1-inch adhesive strips at end; effect similar to clothespin); ice packs do not work; err on side of caution, bring too much equipment; have patient hold emesis basin to catch clots; first have patient blow nose to clear area; can use vasoconstrictor to reduce bleeding and local anesthetic; newer products effective; 2% lidocaine, 1:1000 epinephrine and 2% tetracaine (LET) vasoconstrictor as effective as cocaine, less expensive, and has no adrenergic surge; soak cotton ball in LET, wring out, gently insert with bayonet forceps, wait 10 to 15 min, then remove; apply silver nitrate sticks if bleeding site obvious and bleeding has stopped (useless in active bleeding; random insertion may cause perforation); bleeding site identified 10% of time; gently roll stick over area; avoid large area of eschar (can cause necrosis and perforation); one half-inch wide Vaseline gauze effective; grasp gauze 6 in from end and insert (prevents insertion into back of throat); leave 6 in exposed at other end; speaker has not had success with merocel sponges; can try hemolyzing agents (eg, oxidized cellulose [Oxycel and Surgicel] self-absorbs in 2 to 3 days); balloon “savior” if nothing else works; uncomfortable for patient, use procedural sedation; can cause bradycardia; ensure patient not bleeding before discharge; have patient walk around ED at least twice to create stress; if possible have patient bend forward to tie shoes; coagulation studies not indicated in ED; take good history (reveals whether patient on warfarin); prophylactic antibiotics important because of risk for sinusitis and toxic shock syndrome; amoxicillin drug of choice; remove nonabsorbable pack after 2 to 3 days; pitfalls—failure to apply pressure for adequate time; failure to pack nose properly; failure to have patient perform “walkaround”; failure to prescribe antibiotics; failure to ensure patient not taking aspirin for several days
Nose trauma: x-rays unnecessary; plastic surgeons and otolaryngologists wait until swelling has diminished; decide procedure at that time; x-rays performed for medicolegal reasons; pitfalls—failure to identify and treat septal hematoma (results in saddlenose deformity; drain hematoma by making curvilinear incision); failure to rule out cerebrospinal fluid leak, especially in patient with persistent nasal drainage
SIMPLE PROCEDURES THAT CAN CHANGE YOUR PRACTICE Gregory S. Johnston, MD, Assistant Professor of Emergency Medicine, New York University School of Medicine, New York, NY

Transthecal Digital Block
Technique: inject into tendon sheath; lidocaine travels through sheath and diffuses into digital nerve; equivalent to performing block on dorsal side of finger; procedure—povidone/iodine preparation; 1% lidocaine; look for distal palmar crease; inject 2 to 3 mL lidocaine at 45° angle; sends anesthesia distally into sheath toward finger; use other hand to apply proximal pressure on sheath to prevent backflow; use sterile technique and 25- to 30-gauge needle; resistance to injection suggests needle tip on flexor tendon; pull back slightly and inject; wait 3 to 5 min; no complications reported in literature; advantages—single injection; as effective as traditional block; small amount of anesthetic; no risk of hitting nerve; disadvantage—slightly more painful; theoretic risk for infection (not documented); indications—lacerations; nailbed injuries; foreign bodies; best for second to fifth fingers but also works for thumb; contraindications—infection; flexor tendon synovitis
Literature: first described by Chiu (1990); 420 patients, no complications; Hill (1995)—162 patients, half received transthecal block, half traditional block; both equally effective; minimal differences in pain during administration; Low (1997)—20 volunteers, transthecal and subcutaneous single-injection digital block; slightly more pain during and 24 hr following injections; small differences; suggested transthecal block possibly not as good as regular digital block; Cummings (2004)—25 patients, mapped anesthesia using light-touch and pinprick sensation; found less dorsal anesthesia; not necessarily relevant to clinical practice; Keramidas (2004)—50 patients, compared transthecal digital block with traditional block; slightly more painful with injection and at 24 hr; Hart (2005)—transthecal digital block considered useful technique

Intra-articular Lidocaine for Shoulder Dislocation
Technique: eliminates need for conscious sedation; procedure—sterile technique; cleanse shoulder and inject into joint space (2 cm inferior to lateral edge of acromion) with 18- or 20-gauge needle; literature suggests first aspirating hemarthrosis if present; inject 20 mL of 1% lidocaine over 30 sec; wait 15 to 20 min before attempting reduction; indications— anterior shoulder dislocations; no literature on posterior or inferior dislocations; contraindications—lidocaine allergy; cellulitis over entry site; obese or muscular patients; advantages—simple; shortens ED visit; no sedation required; no recovery period; does not limit other options (eg, conscious sedation); disadvantages—limits muscle relaxation (problematic in apprehensive patient)
Literature: first described by Lippitt in 1991; Matthews (1995)—15 patients; better reduction in intra-articular lidocaine group; Suder (1995)—66 patients; half received intra-articular injections and had good results; half received procedural sedation (high complication rate); American Journal of Emergency Medicine (1999)—29 patients received intra-articular lidocaine; longer period of dislocation period associated with less success with intra-articular lidocaine; Miller (2002)— 15 patients; big cost savings
PROCEDURAL SEDATION AND ANALGESIA Luis M. Lovato, MD, Assistant Professor, the David Geffen School of Medicine at the University of California, Los Angeles (UCLA), and Director of Critical Care, Department of Emergency Medicine, Olive View/UCLA Medical Center, Los Angeles
Goals (American College of Emergency Physicians [ACEP]): sedate patient with or without analgesia; allow patient to tolerate unpleasant procedure; maintain cardiorespiratory function; depress level of consciousness; maintain independent airway control
Patient selection: based on American Society of Anesthesiologists (ASA) classification of physical status; P1 to P6; P1—healthy, no medical problems; P2—inactive or mildly active hypertension; P3—hypertension, diabetes and coronary artery disease (CAD), severe systemic disease; P4—patients with constant threat to life, eg, CAD patient with active chest pain, acidotic diabetic patient; know when to call in consultant
Considerations: patient’s cardiorespiratory stability; length of procedure; previous adverse reactions; assessment of airway; available alternatives (eg, digital block, regional block)
ACEP 2005 clinical policy: recommendation levels—(A) multiple randomized control trials; clinical certainty; (B) strength of evidence suggests best choice; (C) slightly better than expert opinion; personnel—appropriately trained specialist; patient assessment—history; allergies; airway; fasting—recent food intake not contraindication; equipment— oxygen; equipment for advanced airway management; monitoring—close monitoring required; respiratory assessment—check pulse oximetry if patient high-risk patient (may not be necessary); consider end-tidal CO2 monitoring
Speaker’s interpretation of ACEP policy: personnel—do not try procedural sedation and analgesia (PSA) if clinician inexperienced; patient assessment—full history; assess airway; fasting—does not matter; equipment—always be ready for complications; monitoring—monitor closely; respiratory assessment—preoxygenation (on nonrebreather mask for 3 min) and pulse oximetry on all patients on deep sedation
Case 1 (wooden stick vs head): 2-yr-old with deep forehead laceration over eyebrow; no past medical history; no known allergies; weight 15 kg; acting well; mild anxiety and agitation with staff; can “papoose” (restrain) child as reasonable alternative; can use ketamine
Ketamine: class A; actions—sedative, hypnotic, amnestic, and analgesic properties; dosing—intravenous (IV) and intramuscular (IM); reliable; onset/duration—IV onset 1 min, 15-min duration; IM onset 5 min, 30-min duration; side effects—usually not problematic in children; nystagmus (warn parents) and vomiting; cardiovascular stimulation; hypersecretion; emergence delirium; laryngospasm; can cause hypertension, cardiovascular stimulation, ischemia, and hallucinosis in adults; do not use in large-size adults; contraindications—active respiratory infection; hallucinosis present; infants <3 mo of age (laryngospasm likely); advantages—single agent; reliable effect; established safety record; note— concurrent use of atropine in children <5 yr of age controversial
Case 2 (fever and agitation): complicated seizure, not regaining complete consciousness; 12 kg; requires computed tomography and lumbar puncture
Medication choices: fentanyl and midazolam (Versed)—ACEP level B recommendation; titratable; mild, moderate, or deep sedation; commonly available; established safety record; barbiturates—concerns of hypoxia, hypotension, prolonged effect; overall very safe; use when concerned about increased intracranial pressure; propofol—ACEP level B; more incidence of hypoxia, hypotension; dosage unclear; etomidate—ACEP level C; no large-scale pediatric studies; nonstandardized dosing; short acting; dose 15 mg in adults; onset <1 min; duration 10 min; reliable; minimal cardiovascular depression; reduces intracranial pressure; no large studies; requires concurrent analgesic; fentanyl and midazolam—ACEP level B; good combination (fentanyl [opiate] plus midazolam [sedative, hypnotic, amnestic]); quick onset; 30-min duration; mild respiratory depression; mild hypotension; long titration to sedation; propofol—ACEP level B; nonopiate, nonbarbiturate sedative hypnotic; no analgesia; sedation deep and sometimes general; antiemetic and euphoric properties; initial dose 1 mg/kg bolus; titrate to effect with 0.5 mg/kg every 3 to 5 min; quick onset; 10- min duration; decreased blood pressure; respiratory depression; reliable; no myoclonus; reduces intracranial pressure; requires repeat dosing; pain with injection

Suggested Reading

Burton JH et al: Propofol for emergency department procedural sedation and analgesia: a tale of three centers. Acad Emerg Med 13:24, 2006; Chiu DT: Transthecal digital block: flexor tendon sheath used for anesthetic infusion. J Hand Surg [Am] 15:471, 1990; Chudnofsky CR et al: A combination of midazolam and ketamine for procedural sedation and analgesia in adult emergency department patients. Acad Emerg Med 7:228, 2000; Cummings AJ et al: Modified transthecal digital block versus traditional digital block for anesthesia of the finger. J Hand Surg [Am] 29:44, 2004; Godwin SA et al: Clinical policy: procedural sedation and analgesia in the emergency department. Ann Emerg Med 45:177, 2005; Hart RG et al: Transthecal digital block: an underutilized technique in the ED. Am J Emerg Med 23:340, 2005; Hill RG Jr et al: Comparison of transthecal digital block and traditional digital block for anesthesia of the finger. Ann Emerg Med 25:604, 1995; Kosnik J et al: Anesthetic methods for reduction of acute shoulder dislocations: a prospective randomized study comparing intraarticular lidocaine with intravenous analgesia and sedation. Am J Emerg Med 17:566, 1999; Low CK et al: Comparison of transthecal and subcutaneous single-injection digital block techniques. J Hand Surg [Am] 22:901, 1997; Matthews DE, Roberts T: Intraarticular lidocaine versus intravenous analgesic for reduction of acute anterior shoulder dislocations. A prospective randomized study. Am J Sports Med 23:54, 1995; Miller SL et al: Comparison of intra-articular lidocaine and intravenous sedation for reduction of shoulder dislocations: a randomized, prospective study. J Bone Joint Surg Am 84-A:2135, 2002; Miner JR et al: Randomized clinical trial of etomidate versus propofol for procedural sedation in the emergency department. Ann Emerg Med 49:15, 2007; Orlinsky M et al: Comparative study of intra-articular lidocaine and intravenous meperidine/diazepam for shoulder dislocations. J Emerg Med 22:241, 2002; Roback MG et al: Preprocedural fasting and adverse events in procedural sedation and analgesia in a pediatric emergency department: are they related? Ann Emerg Med 44:454, 2004; Ruth WJ et al: Intravenous etomidate for procedural sedation in emergency department patients. Acad Emerg Med 8:13, 2001; Willman EV, Andolfatto G: A prospective evaluation of "ketofol" (ketamine/propofol combination) for procedural sedation and analgesia in the emergency department. Ann Emerg Med 49:23, 2007.

Educational Objectives

The goal of this program is to improve the performance of simple procedures (including procedural sedation) in the emergency department. After hearing and assimilating this program, the clinician will be better able to:
1. Discuss the role of irrigation, soaking, and prophylactic antibiotics in the patient with a simple hand wound.
2. Summarize how to evaluate and treat a patient with an eye injury.
3. Describe a rational approach to the patient with severe epistaxis (nosebleeds).
4. Explain how to perform a transthecal digital block.
5. Summarize the American College of Emergency Physicians policy on procedural sedation and analgesia.

Faculty Disclosure

In adherence to ACCME Standards for Commercial Support, Audio-Digest requires all faculty members to disclose relevant financial relationships within the past 12 months that might create any personal conflicts of interest. Any identified conflicts were resolved to ensure that this educational activity promotes quality in health care and not a proprietary business or commercial interest. For this program, the faculty reported nothing to disclose.

Acknowledgements

Dr. Lex addressed the 16th Annual Emergency Medicine Conference, held September 13-16, 2006, in Las Vegas, NV, and sponsored by Kaiser Permanente. Dr. Johnston addressed Contemporary Concepts in Clinical Emergency Medicine, held June 7-9, 2006, in New York, NY, and sponsored by the Department of Emergency Medicine, New York University School of Medicine, Postgraduate Medical School. Dr. Lovato addressed Advances in Emergency Medicine and Primary Care, held April 19-21, 2006, in Las Vegas, NV, and sponsored by the Olive View–UCLA Department of Emergency Medicine, and the American College of Emergency Physicians, State Chapter of California. The Audio-Digest Foundation thanks the speakers and the sponsors for their cooperation in the production of this program.

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